Dec. 18, 2008 – Can EVOO — extra-virgin olive oil — cut the hazard of breast cancer?
Yes — but as it were the 20% to 30% of breast cancers that express the HER2 particles, recommend thinks about by Javier A. Menendez, PhD, at the Catalan Organized of Oncology in Girona, Spain, and colleagues.
The Spanish analysts pondered why a few ponders appear that the olive-oil-rich Mediterranean count calories cuts breast cancer chance whereas other considers don’t . They theorized that the dynamic compounds in olive oil as it were influence certain cancers.
The breast cancer medicate Herceptin targets the HER2 atom on tumor cells. Seem olive oil compounds have the same target?
Menendez’s group to begin with separated different compounds from EVOO — which, since it is made without warm, keeps most of the olive compounds that are misplaced in more handled, lower quality olive oils.
They found that two sorts of these compounds, secoiridoids and lignans, murdered off HER2-positive human breast cancer cells but had small impact on HER2-negative cells.
They too found that when they bolstered huge sums of EVOO to rats with carcinogen-induced breast cancers, the animals’ tumors got to be less harmful.
But this does not cruel that eating a part of EVOO will anticipate or treat breast cancer.
“Extraordinary caution must be connected” in deciphering their discoveries, Menendez and colleagues caution.
One lesson of EVOO anticancer compounds, the secoiridoids, “quickly part into dormant compounds” when eaten. These compounds likely won’t offer assistance if eaten, but may be a beginning point for improvement of modern breast cancer drugs.
On the other hand, the lignan compounds “may speak to a distinctive atomic situation,” Menendez and colleagues recommend. In mouse-feeding considers, tumor tissues gather lignans, “in this way proposing that the anti-cancer movement of lignans may be due to their coordinate neighborhood impacts on the breast cancer tissues.”
A later think about recommended that eating flaxseed is advantageous to ladies with recently analyzed breast cancer. Flaxseed has tall lignan concentrations.
Indeed so, Menendez and colleagues note that much more consider will be required some time recently specialists can prescribe EVOO for breast cancer anticipation or treatment.
The Menendez think about shows up within the open-access diary BMC Cancer.
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